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Mona Mostafa Mohamed

Mona Mostafa Mohamed

Professor of Cell and Cancer Biology 
 

Biography

Dr. Mona Mostafa Mohamed is Professor of Cell and Cancer Biology, Founder and Director of the Cancer Biology Research Laboratory (CBRL), Faculty of Science, Cairo University, Egypt (http://cbrl.cu.edu.eg/). The Senior Academic Director of International Sector, Galala University, Suez, Egypt.

Upon completion of her doctorate at Cairo University, Dr. Mohamed was competitively selected for a prestigious Postdoctoral Avon Foundation- American Association for Cancer Research (AACR) International Award in breast cancer research (2005-2007), at School of Medicine, Pharmacology Department, Wayne State University, Detroit, MI, USA. During her postdoctoral Dr. Mohamed published a “Nature” paper in 2006 as the first author. Dr. Mohamed was the first women at Cairo University to publish in Nature as a first author. Dr. Mohamed “Nature” paper in 2006 increased Cairo University ranking to be included in the top 500 Universities all over the world. According to World Universities Shanghai Ranking’s “Nature” paper impact in university ranking is equivalent to Nobel Prizes.

In 2008 Dr. Mohamed was awarded a start-up fund from Avon foundation, USA to establish the first specific breast cancer biology research lab in Egypt. Dr. Mohamed received several grants from different international organizations such as: 1) Avon Foundation-USA, 2) NIH-Fogarty-USA [2 grants], 3) USA-Egypt joint grants, 3) USA-Egypt joint grants and, 4) European Commission (Horizon 2020).

Dr Mohamed’s research interest is studying breast cancer disease pathogenesis by using advanced molecular and cellular approaches to investigate whether breast cancer patients’ variability in tumor microenvironment genome/proteome and inflammatory mediators may alter clinical manifestations of the disease. Recently Dr Mohamed’s lab is utilizing highly sophisticated research approaches combined with cutting edge bioinformatics and artificial intelligence tools to analyze cellular and molecular alterations of patients derived ex-vivo models) to identify druggable pathways and targets can be presented for pharmaceutical industry for clinical trials (Funded by NIH-Fogarty).In 2023, Dr Mohamed’s lab is the first worldwide to establish patient derived explants (PDEs) Ex-vivo model for inflammatory breast cancer patients (https://pubmed.ncbi.nlm.nih.gov/36592055/).

Dr Mohamed’s main local, national, and international collaborative research aims is to improve treatment outcomes and breast cancer patient survival, by moving toward more accurate approaches to understand how patient biology may alter disease progression. Dr. Mohamed has supervised 43 MSc and 11 PhD students’ theses, her students got postdoctoral positions in USA, Germany, UK, France and Canada. Dr. Mohamed mentored her students to publish peer review articles as first corresponding authors.

Furthermore, Dr. Mohamed supervised 108 graduation projects from 3 Egyptian Universities [Cairo University, University for Modern Sciences and Arts (MSA), Galala University (GU)] and Dr Mohamed trained students from different countries all over the world and arranged international students scientific exchange mobility programs between different countries. Dr Mohamed’s accomplishments in cancer research are evident by high-quality publications (more than 53 papers), track record of funding, and 2/2 internationally recognized collaborative research programs. In collaboration with highly ranked worldwide universities in USA, Germany, Canada, UK and France.

Because of Dr. Mohamed scientific achievements, she had been awarded several awards for example, in 2012, Dr Mohamed was selected by U.S. State Department to be inducted into the Women in Science Hall of Fame (https://jo.usembassy.gov/women-in-science-hall-of-fame-2012/cairo-mona-mostafa-mohamed/). In 2014, Dr Mohamed received Arab Women Organization Prize in Science and Technology. In 2021, Dr Mohamed received Excellence Award for Arab Women in Medicine by League in Arab States, the ceremony was in EXPO Dubai 2020. In 2022, Dr Mohamed was awarded Women in Science: BioScience Scientists Awards.

Area Of Research

  • Understanding the biology of breast cancer such as locally advanced breast cancer (LABC).
  • Metastatic breast cancer (MBC) and inflammatory breast cancer (IBC). Utilizing advanced biotechnology approaches in genetics.
  • Epigenetics, cell biology, molecular biology, immunology, cancer biology, cell & tissue culture.
  • Life cell imaging technology and stem cells characterization to identify specific diagnostic and prognostic disease markers and introduce new target therap.

Awards / Honorable Mentions

  • Honored by the Ministry of Culture Egypt on Women’s Day for her Scientific Achievements. 2019
  • Received Arab Women Organization prize in Science and Technology. 2014
  • Honored by Alexandria Regional Center for Women’s Health and Development, Alexandria, Egypt 2013
  • Women in Science Hall of Fame, U.S. Department of State. 2012
  • Awarded “Best Abstract” prize in the Middle East Best of CTRC-AACR San Antonio Breast Cancer Symposium King Abdulaziz Medical City (KAMC), Saudi Arabia. 2011
  • Awarded Cairo University “Nature” publication prize. 2007
  • Awarded John F. Perkins, Jr. Memorial Award from American Physiological Society. 2006
  • Selected as a recipient “Visiting Scholars in Global Infectious Diseases Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA, USA. 2005

Publications